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A Current Affair’s “ADHD breakthrough”: bona fide news or unethical advertising?

Vitamin and nutritional supplement company, Blackmores, has been in trouble in China recently, reportedly incurring an AUD 65,000 fine after some of its marketing material was found to have breached Chinese “Truth in Advertising” laws.

Spruiking of a Blackmores product, the marine oil extract Lyprinol®, is also raising some eyebrows here in Australia, after ABC’s Media Watch picked up on some problems with an episode of A Current Affair, which labelled Lyprinol® an “ADHD breakthrough.”

But this wasn’t advertising. Or was it?

In the post below, Dr Ken Harvey follows the trail of the A Current Affair story, exposing the conflicts of interest, sloppy reporting and ethical failures along the way.

It’s a post that takes on increased importance in the light of revelations this week, that another vitamin company has called on the federal government to change the way advertising in the complementary medicines industry is regulated. As part of its pre-budget submission, Swisse reportedly suggested that, rather than the Therapeutic Goods Administration,  the Australian Competition and Consumer Commission and Advertising Standards Bureau should deal with advertising claims, compliance and complaints of the sector.


Ken Harvey writes:

Harvey1
Screenshot: ACA “ADHD BREAKTHROUGH” Feb 15 2017

On February 15, 2017, Channel NINE aired an episode of A Current Affair that raises important issues about the ethics of current affairs program journalists, university researchers and complementary medicine companies, and the impact of such programs on the public.

The research: Lyprinol® for ADHD

The program was based on recent research by the Centre for Human Psychopharmacology, Swinburne University of Technology. Their published paper reported the results of a randomised, double-blind, placebo-controlled trial of marine oil extract (PCSO-524® or Lyprinol®, a standardised lipid extract of the New Zealand green-lipped mussel), on the symptoms of 144 children diagnosed with attention-deficit hyperactivity disorder (ADHD).

Professor Con Stough was the senior author of the paper, which included a statement that he had received a grant to fund the study from Pharmalink Pty Ltd, the company who license Blackmores to market Lyprinol®.

The results of the randomised controlled trial “did not support the hypothesis that Lyprinol® improves parental reports of hyperactivity, inattention and impulsivity in children ages 6 to 14 years over placebo” (the study’s pre-specified primary outcome measure).

These results were in accord with a 2012 Cochrane review of “Polyunsaturated fatty acids (PUFA) for attention deficit hyperactivity disorder (ADHD) in children and adolescents” which concluded that there was little evidence that PUFA supplementation provided any benefit for the symptoms of ADHD in children and adolescents.

The ACA program: “ADHD breakthrough”

Harvey2
Screenshot: ACA “ADHD BREAKTHROUGH” Feb 15 2017

Regardless of these research findings, the Nine “A Current Affair (ACA)” story was headed, “ADHD breakthrough”. The voiceover started with, “The surprising medical discovery that has the potential to change lives for ADHD sufferers. Australian researchers have uncovered the hidden possibilities of a simple, over-the-counter anti-inflammatory. Early results look promising”. The screen then showed the words “ADHD Breakthrough” against a Blackmores Lyprinol® pack and capsules.

The program then aired video testimonials from several young men, “I can socialise better, I can exercise better, I can just think so much clearer.” “My schoolwork has improved since I’ve been taking it,” and a mother, “I was just surprised that something which is so readily available worked as well as it did without any negative effects”. This was followed by more screen shots of the Blackmores Lyprinol® pack and capsules.

Next came the voiceover, “It’s been more than six years in the making …” (clear screen shots of a Blackmores Lyprinol® pack shown) … “and finally researchers say they have made a breakthrough”.

A video of Swinburne lab and and EEG tracing appeared on screen. Professor Con Stough said, “The results are pretty clear and they are promising”, then more screen shots of a pile of Blackmores Lyprinol® packs, and a voice over saying, “A natural treatment for ADHD that costs less than $20 a week. It sounds too good to be true but not anymore.”

Upon cutting to shots on a New Zealand green lipped mussel farm, there were more claims, more testimonials and more claims. Mother: “I was looking at the survey results from the study and I was really pleased to see that it was so effective for children that were on no other medication.”

Cut to Professor Con Stough who said, “We randomised 144 children with high hyperactivity or inattention and these are behaviours that were causing them a lot of trouble in school and we randomised them to two groups, one in which they took Lyprinol® for 14 weeks. The other group was placebo for 10 weeks”.

Voice over: “they found a 34% improvement in bad behaviour at home, a 13% improvement in attention and a 10% improvement in hyperactivity,” with these figures reiterated on the screen followed by more testimonials and more pack shots of Blackmores Lyprinol®.

Screenshot: ACA "ADHD BREAKTHROUGH" Feb 15 2017
Screenshot: ACA “ADHD BREAKTHROUGH” Feb 15 2017

Cut to GP Ross Walker: “It’s not that expensive and it has been proven to be effective…”

The program ended with “ADHD breakthrough” superimposed on a voiceover, “Now if you are thinking about changing your child’s medication always consult your doctor first.”

Hardly a “breakthrough”

After seeing the program I contacted Professor Stough, who  told me, “I was interviewed for about 30 minutes where I described in detail the methodology and limitations of the study… However, “A Current Affair” used two sentences… We never claimed it was breakthrough when I was interviewed. I stressed it [the study] should be replicated and that the effects were mostly seen in sub-ADHD symptom participants.”

In the published paper, the authors had reported,

“Analysis of the primary outcome found no significant differences between treatment groups on CPRS following 14-week supplementation.”

So, where did the, “34% improvement in bad behaviour at home, a 13% improvement in attention and a 10% improvement in hyperactivity” come from?

These figures are not found in the paper. I can only conclude that they were derived from the post-hoc, sub-sample analysis of Conners’ Parent Rating Scale (CPRS) data. This is reported in the paper thus,

“Non-combined type (NCT) (N = 43; PCSO-524® n = 23) analysis revealed a significant improvement in children who consumed PCSO-524® on CPRS scores of hyperactivity, learning abilities and improved behaviour at home, as well as improvements on DSM scores of attention and hyperactivity”.

Far from concluding that these results constituted a “breakthrough”, the authors wrote that their “exploratory post hoc analysis of the primary outcome” indicated “promise for the use of PCSO-524® in the treatment of symptoms of inattention, hyperactivity and impulsivity in children and adolescents with or without ADHD displaying less severe behavioural symptoms,” and that there was a need for further research.

Misleading and unethical

In my opinion, this ACA program is misleading, unethical advertising, thinly disguised as news. It targets a vulnerable population, parents of children labelled as having ADHD, misrepresents research results and promotes a product that has been proven to have no benefit over a placebo.

Harvey3
Screenshot: Bite communications website newsfeed, Feb 15 2017

So, how did the Nine ACA “ADHD breakthrough” story get it so wrong?

It seems that a communications company was involved. Bite communications, a healthcare public relations company, breathlessly announced on their web site before the episode screened,  “Great story on Swinburne University of Technology’s breakthrough research on ADHD on tonight’s A Current Affair. Go team Bite!”

But, who briefed and paid Bite communications? Given the prominence the story gave Blackmores Lyprinol® it is hard to believe that Blackmores was not involved. Dr Ross Walker, who appeared on the program has also appeared on the Blackmores Institute web site. He has also had upheld complaints about his endorsement of other products.

In addition, Richard Henfrey, a member of the Blackmores management team, sent an email to a TGA stakeholders group saying, “I thought you may like to see this story from A Current Affair last night. I think you will all agree that this story, which has been in preparation for some time, represents exactly the sort of responsible approach to new research evidence that we have all been arguing for”.

I didn’t think so, neither did Professor Jon Jureidini (a child psychiatrist) who has submitted formal complaints about the program, and neither did Paul Barry who ridiculed this program on ABC Media Watch.

And what about Professor Con Stough and the co-authors of his paper at the Centre for Human Psychopharmacology, Swinburne University of Technology? Despite Professor Stough’s protest at being misrepresented, at the very least, the Swinburne team must have provided ACA and/or Bite communications with the contact details of the patients interviewed.

Also, who apart from the Swinburne team, had access to the raw research data that allowed the percentage figures to be derived and highlighted on the ACA program?

In addition, although the Swinburne study was well conducted, in my opinion, the title and abstract of the published paper ignored the null result of the primary aim of the study and placed undue emphasis on post-hoc subsample results (data dredging) which the ACA focused on.

Screenshot: Bite Communications Facebook page.
Screenshot: Bite Communications Facebook page.

This paper, and the ACA program, appears to be yet another example of how industry funding of research can skew research results.

Finally, the journalists involved in NINE ACA have an unenviable reputation for hyping products without scrutiny. Their promotion of Peter Foster’s Sensaslim was a classic in this genre and they keep on keeping on as this “ADHD breakthrough” story shows. In my opinion, no academic who values their reputation should ever appear on this program.


In the preparation of this article, Croakey sought responses from Blackmores and from Professor Con Stough.

We asked Blackmores:

  1. Did you engage and pay Bite Communications to promote Lyprinol® and, if so, did you engage and pay them to provide A Current Affair with the information to produce the “ADHD Breakthrough” segment of A Current Affair?
  2. The program included patients who provided testimonials. Do you know who sourced the patients? Was it Blackmores, Bite Communications or the Swinburne team?
  3. There were some statistics in the A Current Affair program, “a 34% improvement in bad behaviour at home, a 13% improvement in attention and a 10% improvement in hyperactivity”, that were not in the research paper. Do you know how these statistics were derived, and who provided them A Current Affair?

Blackmores had not replied at the time of publication.

We asked Professor Stough:

  1. Do you know who provided the patients for use in the testimonials?
  2. The statistics quoted on the program of “a 34% improvement in bad behaviour at home, a 13% improvement in attention and a 10% improvement in hyperactivity” do not appear in your research paper. Did your team derive these statistics or provide additional data to Bite Communications or A Current Affair for use in the program? Do you know how the statistics were derived?
  3. Do you believe the representation of your findings on the A Current Affair segment was accurate and balanced?

We received the following response:

A Current Affair did not accurately describe the outcomes of my research. The publication in Psychopharmacology outlines full details of the results. I always try to keep the facts of the study at the forefront but at the end of the day, I have no control over what is published or put on air.

*Dr Ken Harvey is an Associate Professor at the Department of Epidemiology and Preventive Medicine, Monash University.

 

 

 

 

 

 

 

Comments 2

  1. Wonderful article and keep up the good work. Funding of university research by the complementary medicine industry is becoming a massive concern – the only way to combat this will be to continue to expose them, as was done with this article.

  2. PostScript:

    On 31 May 2017 the Australian Communications and Media Authority (ACMA) concluded that the licensee did not breach clause 3.3.1 of the Code, ‘In broadcasting a news or Current Affairs Program, a Licensee must present factual material accurately and ensure viewpoints included in the Program are not misrepresented’.

    In making this finding, the ACMA did not consider whether the media release, the findings by the researchers, or their methods, were scientifically supportable (which was the thrust of the complaint), merely that it was ok for Channel Nine to presume that a media release was a reputable source of information!

    On 27 March 2018, following FOI requests, the TGA confirmed that their Advertising Compliance Unit (ACU) did investigate a complaint forwarded to them by the Complaint Resolution Panel .

    The ACU wrote to Channel Nine regarding the segment, and indicated that its preliminary view was that the segment may have satisfied the definition of ‘advertisement’ in the Therapeutic Goods Act 1989 and that the advertisement may have breached the Therapeutic Goods Advertising Code.

    The ACU requested deletion of the following material which contained information presented in the broadcast, and, at that time, was still available:
    · A tweet posted by the ACA twitter account
    · A story on the 9 News website
    · Copies of the broadcast on digital streaming services, such as YouTube.

    While no final position was reached in relation to the advertising requirements, Channel Nine removed the material referred to above.

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